3,541 research outputs found

    External liquid-spray cooling of turbine blades Patent

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    External device for liquid spray cooling of gas turbine blade

    Prospective genetic screening decreases the incidence of Abacavir hypersensitivity reactions in the Western Australian HIV cohort study

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    Abacavir therapy is associated with significant drug hypersensitivity in ∼8% of recipients, with retrospective studies indicating a strong genetic association with the HLA-B*5701 allelle. In this prospective study, involving 260 abacavir-naive individuals (7.7% of whom were positive for HLA-B*5701), we confirm the usefulness of genetic risk stratification, with no cases of abacavir hypersensitivity among 148 HLA-B*5701–negative recipients

    Climate displacement and resettlement: the importance of claims-making ‘from below’

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    This is the author accepted manuscript. The final version is available from Taylor & Francis via the DOI in this recordClimate-induced population displacement and resettlement is an ongoing problem around the world, and one that is being exacerbated by climate change. To date, most attempts to address this problem have taken a top-down approach in which international justice, legal and humanitarian frameworks are extended ‘downwards’ by policymakers and governments to local populations. However, there has been limited systematic work that emphasizes the abilities of affected peoples themselves to develop and formulate their own justice-based solutions. This paper presents an analytical framework for thinking about ‘bottom-up’ claims-making that emphasizes naming, blaming, claiming and framing. The framework enables claims-making to be distinguished from other forms of community-based agency, such as adaptation. The paper also suggests a normative framework to support policymakers and practitioners in helping communities facing displacement to make claims. The normative framework focuses on the barriers to, and opportunities for, claims-making ‘from below’

    The mystery of the missing warbler

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    Social Support Seeking And Early Adolescent Depression And Anxiety Symptoms: The Moderating Role Of Rumination

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    This study examined how social support seeking and rumination interacted to predict depression and anxiety symptoms 6 months later in early adolescents (N = 118; 11-14 years at baseline). We expected social support seeking would be more helpful for adolescents engaging in low rather than high levels of rumination. Adolescents self-reported on all measures at baseline, and on depression and anxiety symptoms 6 months later. Social support seeking predicted fewer symptoms of depression and anxiety at low rumination levels but was not associated with benefits as rumination increased. For depression symptoms, social support seeking predicted more symptoms at high rumination levels. Results were stronger for emotion-focused than problem-focused support seeking and for depression compared with anxiety symptoms. These findings suggest that cognitive risk factors like rumination may explain some inconsistencies in previous social support literature, and highlight the importance of a nuanced approach to studying social support seeking

    Self vs. Parent: Factors Influencing Likelihood of Hiring a Healthcare Advocate

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    Objective: To determine how the factors that may lead an individual to hire a healthcare advocate to aid him/herself in navigating the healthcare system when dealing with chronic or complex health issues differ from the factors that are considered when deciding to hire a healthcare advocate for one’s parent.Methods: 1,740 randomly selected participants completed a brief vignette-based questionnaire that indicated their likelihood of hiring an HCA for oneself or a parent. Confirmatory factor analysis and structural equation modeling were used to test the effects of predisposing, enabling, and illness factors on the predicted likelihood.Results: Although neither model fit well statistically, both fit well descriptively. The direct path from predisposing to enabling factors and the indirect path from predisposing factors to illness level were significant in both models. Discussion: Understanding the factors that influence the decision to hire an HCA could help health providers target patients who are most likely to use HCA services, thereby reducing the burden on the healthcare system and improving quality of care
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